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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1631-1640 of 11547

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  1. Agili-C™ Implant Performance Evaluation

    Rochester, MN

  2. Monitoring Neoadjuvant Chemotherapy Of Breast Cancer Using 3D Subharmonic Aided Pressure Estimation

    Rochester, MN

  3. Testing An Active Form Of Tamoxifen (4-hydroxytamoxifen) Delivered Through The Breast Skin To Control Ductal Carcinoma In Situ (DCIS) Of The Breast

  4. A Study of the Thalamus Using Deep Electrode EEG to Better Understand its Participation in the Beginning or Spreading of Seizures

    Rochester, MN

  5. Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection

    Rochester, MN

  6. A Study To Investigate The Long-Term Safety Of ZX008 (Fenfluramine Hydrochloride) Oral Solution In Children And Adults With Epileptic Encephalopathy Including Dravet Syndrome And Lennox-Gastaut Syndrome

    Rochester, MN

  7. A Study Of Inhaled GB002 For Treatment Of WHO Group I Pulmonary Arterial Hypertension

    Jacksonville, FL

  8. A Study To Evaluate Intravenous Iloprost In Subjects With Symptomatic Raynaud's Phenomenon Secondary To Systemic Sclerosis

    Rochester, MN

  9. A Study To Evaluate The Efficacy And Safety Of Colchicine On Coronavirus SARS-CoV2 Positive Adults

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. A Trial To Assess Effectiveness And Safety Of Octreotide Subcutaneous Depot In Patients With GEP-NET

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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