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Clinical Studies
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Accelerated Resolution Therapy For Early Maladaptive Grief: A Clinical Trial
Rochester, Minn.,
Jacksonville, Fla.,
Scottsdale/Phoenix, Ariz.
The purpose study is to test the effects of accelerated resolution therapy (ART) on pre-loss grief and prolonged grief disorder among older adult family caregivers (FCGs). Additionally, to better understand predictors of response to ART, and cognitive processes that occur among grieving individuals following ART.
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Factors Associated with Grief Among Older Adult Family Caregivers
Jacksonville, Fla.
The purpose of this study is to evaluate the trajectory of loss and grief over 12 months, the risk factors associated with high levels of pre-loss grief, and the preliminary effectiveness of ART for treatment of high levels of pre-loss grief among family caregivers (FCG) of persons nearing the end of life.
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Group Meaning-Centered Psychotherapy For Caregivers Of Patients With Advanced Cancer
Rochester, Minn.,
Jacksonville, Fla.
This clinical trial assesses the acceptability and feasibility of a virtual group Meaning-Centered Psychotherapy for Cancer Caregivers (MCP-C) and its effect in improving the wellbeing of caregivers of patients with advanced cancer. Caregivers often suffer from significant existential distress, which includes feelings of hopelessness, demoralization, burden, loss of meaning and dignity, and a decreased will to live. MCP-C seeks to help caregivers connect to meaning and purpose despite the challenges of caregiving and helps caregivers understand how sources of meaning may help with symptoms of burden and reduce despair. Participating in MCP-C may help improve sense of personal meaning, spiritual well-being, and mood in caregivers of patients with advanced cancer.
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mHealth app for caregiver instruction in manual therapy for chemotherapy-induced peripheral
neuropathy.
Jacksonville, Fla.
The purpose of this study is to assess the impact of home-based utilization of the PNR program on cancer survivors with CIPN and caregivers applying the instruction, and to develop a mobile application that will deliver the instructional program.
Closed for Enrollment
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Accelerated Resolution Therapy for Cancer Related Trauma and Distress: A Pilot Study
Jacksonville, Fla.
The purpose of this study is to quantitatively evaluate accelerated resolution therapy (ART) for treatment of cancer distress and psychological trauma.
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Accelerated Resolution Therapy in Cancer and Palliative Care: A Program Evaluation
Jacksonville, Fla.
The following research questions will guide this study: 1) Is ART feasible and acceptable for use with distressed patients and/or family caregivers in oncology and palliative care clinical settings? 2) What is the mean dose of ART provided to distressed patients and/or family caregivers? 3) What are the patient and family stressors that result in a recommendation for ART? 4) Does ART reduce symptoms of psychological trauma, anxiety and depression, when used with distressed patients and family caregivers in oncology and palliative care clinical settings? 5) Does ART improve resilience when used with distressed patients and family caregivers in oncology and palliative care clinical settings?
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Associations of Fatigue and Chemotherapy-Induced Nausea with Changes in Gut Microbiome Composition Profiles
Rochester, Minn.,
Mankato, Minn.,
Jacksonville, Fla.,
Scottsdale/Phoenix, Ariz.,
Albert Lea, Minn.
The long-term goal of this study is to alleviate the occurrence of CIN and fatigue and to improve chemotherapy treatment outcomes. The identification of associations between fatigue, CIN and chemotherapy-induced changes in gut microbiome composition profiles will increase our understanding of these mechanisms that underlie patient symptom experience. An increased understanding of the underlying mechanisms will provide targets for the development of novel interventions to help alleviate fatigue and CIN.
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Cancer Distress, Psychological Trauma, and Resiliency in Hospitalized Hematopoietic Stem Cell Transplant Patients, a Descriptive Study
Jacksonville, Fla.
The purpose of this study is to better understand the distress experience of hospitalized patients undergoing hematopoietic stem cell transplant (HSCT), and to examine the relationship between cancer distress, psychological trauma, and resiliency over time.
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Describing the Determinants and Effects of Variation in the Adoption and Use of the NOHARM Pain Management Intervention Among Diverse Surgical Practices
Rochester, Minn.,
Jacksonville, Fla.
The purpose of this study is an effort to enrich the ongoing NOHARM pragmatic trial. NOHARM AIM 3 will use a mixed methods analysis of patient and care team factors that affect the adoption, implementation and use of the NOHARM intervention using Epic reports, conduct chart reviews and patient interviews, as well as obtain feedback via suveys.
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Post-Traumatic Stress Disorder Symptoms among Intensive Care Unit Nurses.
Rochester, Minn.,
Jacksonville, Fla.
The purpose of this project is to improve understanding of post-traumatic stress disorder (PTSD) symptoms and their effect on mental well-being among intensive care unit (ICU) nurses, as well as to pilot test a novel treatment for PTSD among ICU nurses. ICU nurses are at high risk of developing PTSD due to regular and ongoing exposure to death and tragedy. This study will lead to improvements in understanding of the prevalence of PTSD and associated factors among nursing staff, as well as the preliminary effects of an intervention to ameliorate it.
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Subjective and Objective Measures of Peripheral Neuropathy and their Relationship to Symptom Severity and Physical Function in Gastrointestinal Cancer Patients Receiving Oxaliplatin
Jacksonville, Fla.
The purpose of this study is to prospectively evaluate the development of neuropathy symptoms and corresponding changes in physical function in persons receiving oxaliplatin based chemotherapy.
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Survivorship Experiences Post Cancer Treatment: Needs of Patients and Caregivers (SEPCT)
Jacksonville, Fla.
The purpose of this study is to evaluate sexual well-being in minority women who have been diagnosed with cancer, and their partners.
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Symptoms and Quality of Life Issues in Women Living with Metastatic Breast Cancer
Jacksonville, Fla.
The purpose of this study is to gain an understanding of the lived experiences of symptoms and quality of life issues experienced by women with metastatic breast cancer.
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