Amanda R. Bonikowske, Ph.D.

Closed for Enrollment

• Comorbid Insomnia and Sleep Disordered Breathing in Patients Undergoing Cardiac Rehabilitation: Prevalence and Impact on Cardiovascular Risk Profile Rochester, Minn.

  The objectives of this study are to examine the prevalence of comorbid sleep disordered breathing (SDB) and insomnia in post-MI patients enrolled in cardiac rehabilitation (CR), to assess whether post-MI CR patients with comorbid SDB and insomnia exhibit a more unfavorable CV profile than those without, and to determine whether post-MI CR patients with comorbid SDB and insomnia show less adherence to CR than those without.

• Efficacy of Prescription Methods for High-intensity Interval Training in Patients Enrolled in Outpatient Cardiac Rehabilitation (PRO-HIIT) Rochester, Minn.

  The main purpose of the study is to examine the effect of two different high intensity interval training (HIIT) prescription approaches on improving fitness, heart function, and the ability of the body's muscles to receive oxygen. The two approaches of the same total exercise durston will include: 1) HIIT with progressively increased interval durations (PRO-HIIT) versus 2) HIIT with constant shorter interval durations (CON-HIIT). The study hypothesis is that the progressively increased interval duration at high-intensity (PRO-HIIT) will result in a greater increases in fitness, heart function, and the ability of the body's muscles to receive oxygen in patients enrolled in cardiac rehabilitation. 

• Objective Measure of Physical Activity and Sedentary Behavior During Cardiac Rehabilitation: Are Patients Achieving Recommendations/ Guidelines? Rochester, Minn.

  The purpose of this study is to measure overall activity (sedentary-to-high intensity) during rehab and at 1 year follow-up.  

• Objective Measure of Physical Activity and Sedentary Behavior During Cardiac Rehabilitation: Are Patients Achieving Recommendations/Guidelines (PA-CR) Rochester, Minn.

  The main purpose of this study is to measure overall activity (inactive to high intensity) during a 12-week cardiac rehabilitation program.  Furthermore, during the COVID-19 pandemic, cardiac rehabilitation has become home-based. Therefore, a secondary purpose of this study is to determine whether there are differences in physical activity levels between home-based and center-based cardiac rehabilitation.

• The Effect of Interval Training Using Body Weight on Body Composition in Sedentary Overweight and Obese Adults Rochester, Minn.

  Body-weight based interval training (IT) performed 3 times per week will lead to reductions in abdominal adiposity and reduce overall body fat percentage in overweight and obese sedentary adults more effectively than moderate intensity continuous training (MICT). Body-weight interval training will improve exercise capacity (peak VO2) in overweight/obese adults.