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Clinical Studies
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ART of SABR: A Randomized Phase II Trial of Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer: Two Versus Five Fractions
Rochester, Minn.,
Mankato, Minn.,
La Crosse, Wis.,
Albert Lea, Minn.,
Eau Claire, Wis.
The purpose of this study is to assess treatment-related, patient-reported early QOL changes after stereotactic ablative body radiotherapy (SABR) using the EPIC-26 bowel and bladder domains.
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Randomized Phase II Stereotactic Ablative Radiation Therapy (SABR) for Metastatic Unresected Renal Cell Carcinoma (RCC) Receiving Immunotherapy (SAMURAI) (SAMURAI)
Rochester, Minn.
The purpose of this study is to determine whether the addition of stereotactic ablative radiotherapy (SABR) to the primary tumor in combination with immunotherapy improves outcomes compared to immunotherapy alone in patients with metastatic, unresected, renal cell carcinoma (RCC). The primary endpoint is nephrectomy and radiographic progression-free survival (nrPFS) with progression determined as per iRECIST criteria.
Closed for Enrollment
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A Prospective Comparative Study of Outcomes with Proton and Photon Radiation in Prostate Cancer (COMPPARE) (COMPPARE)
Rochester, Minn.,
Mankato, Minn.,
La Crosse, Wis.,
Jacksonville, Fla.,
Eau Claire, Wis.
The purpose of this study is to determine if prostate cancer patients treated with proton therapy as compared to IMRT experience improved QOL (validated EPIC instrument measuring bowel, urinary, and sexual QOL).
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Prospective Evaluation of Hypofractionation Proton Beam Therapy with Concurrent Treatment of the Prostate and Pelvic Nodes for Clinically Localized, Intermediate or High Risk Prostate Cancer
Rochester, Minn.,
Scottsdale/Phoenix, Ariz.
The purpose of this study is to evaluate the safety and effectiveness of a moderate hypofractionation regimen of proton beam therapy with same time treatment of the prostate, seminal vesicles, and the regional pelvic nodes for patients who have clinically localized, high risk or unfavorable intermediate risk prostate cancer.
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Randomized Phase II Stereotactic Ablative Radiation Therapy (SABR) for Metastatic Unresected Renal Cell Carcinoma (RCC) Receiving Immunotherapy (SAMURAI) (SAMURAI)
Jacksonville, Fla.
The purpose of this study is to determine whether the addition of stereotactic ablative radiotherapy (SABR) to the primary tumor in combination with immunotherapy improves outcomes compared to immunotherapy alone in patients with metastatic, unresected, renal cell carcinoma (RCC). The primary endpoint is nephrectomy and radiographic progression-free survival (nrPFS) with progression determined as per iRECIST criteria.
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