Panos Korfiatis, Ph.D.

Closed for Enrollment

• A Phase 2, Randomized Double-Blind, Placebo-Controlled, Multi-Center Study To Assess The Efficacy, Safety, And Tolerability Of Oral LPCN 1148 In Male Subjects With Cirrhosis Of The Liver And Sarcopenia Scottsdale/Phoenix, Ariz., Rochester, Minn.

  The purose of this study is to assess the effectiveness, safety, and tolerability of LPCN 1148 in men with cirrhosis of the liver and sarcopenia.

• Evaluation Of Organ At Risk Segmentation For Prostate Radiotherapy Utilizing A UNET Variant Architecture Rochester, Minn.

  The purpose of this study is to determine:  if the artificial intelligence (AI)-generated results are less arduous than manual tracing by radiation oncologist, and the non-inferiority of the quality of AI vs. manual tracing.  These aims will be evaluated in a clinical environment to investigate the impact of an AI algorithm on the clinical workflow. 

  Radiotherapy treatment planning requires precise calculations of radiation exposure, not only for the target volumes (tissue containing malignancy), but of nearby organs-at-risk (OARs), in which the exposure needs to be minimized. Manual segmentation of these organs is a time-consuming task with high interobserver variability. Producing these segmentations automatically will reduce the time required for treatment planning and improve the interobserver variability.