Faculty

Vijay K. Ramanan, M.D., Ph.D.

Clinical Studies

Alzheimer's National Registry For Treatment And Diagnostics Rochester, MN
The purpose of this study is to collect longitudinal clinical and safety data for enrolled patients being evaluated for or treated with novel FDA-approved Alzheimer's disease therapies.
An Open-label, Single Ascending Dose Study To Evaluate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Intrathecally Administered PrP-siRNA In Adult Patients Diagnosed With Symptomatic Prion Disease. Rochester, MN
The purpose of this trial is to evaluate safety, tolerability, pharmacokinetics and pharmacodynamic impact of PrP-siRNA in symptomatic prion disease patients.
Biomarkers And Rates Of Progression In Dementia (Bio-RaPID) Jacksonville, FL Rochester, MN
The purpose of this study is to evaluate, genetically characterize, and apply serial multimodal biomarkers in patients to determine the patient- and disease-specific factors that associate with Alzheimer disease (rpAD) and AD-related dementias (rpADRD).

ALSENLITE: AN OPEN-LABEL PILOT STUDY OF SENOLYTICS FOR ALZHEIMER DISEASE Rochester, MN
The purpose of this study is to measure target engagement in cerebrospinal fluid (CSF) and blood, and to establish the feasibility and safety of Dasatinib plus Quercetin treatment in adults with early stage but symptomatic Alzheimer's Disease (AD) to inform and select the best blood, CSF, urine, and other analyses to conduct in banked samples from a larger Phase 2b clinical trial.