Biomarkers and Rates of Progression in Dementia (Bio-RaPID)

Overview

About this study

The purpose of this study is to evaluate, genetically characterize, and apply serial multimodal biomarkers in patients to determine the patient- and disease-specific factors that associate with Alzheimer disease (rpAD) and AD-related dementias (rpADRD).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age ≥ 18 years (no upper limit)
Meets RPD criteria at consent
Rapidly progressive dementia attributed to AD/ADRD
Has a reliable collateral source (spouse/partner, adult child, close friend)
Legally authorized representative consenting to study participation
Participant willing to complete study-specific procedures

Exclusion Criteria:

Rapidly progressive dementia attributed to acute large-territory cerebral infarction (stroke), CNS infection, or prion disease

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 09/09/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Vijay Ramanan, M.D., Ph.D.	Open for enrollment	Contact information: David Kochan (507) 293-2519 Kochan.David@mayo.edu
Jacksonville, Fla. Mayo Clinic principal investigator Gregory Day, M.D.	Open for enrollment	Contact information: Alzheimer's Disease Research Center (507) 284-1324

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Vijay Ramanan, M.D., Ph.D.

Open for enrollment

Contact information:

David Kochan

(507) 293-2519

Kochan.David@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Gregory Day, M.D.

Open for enrollment

Contact information:

Alzheimer's Disease Research Center

(507) 284-1324

More information

Publications

Publications are currently not available

Clinical Trials