Mira T. Keddis, M.D.

The purpose of this study is to investigate syndecan-1 expression levels on immune cells, especially pDCs, in systemic lupus erythematosus (SLE) patients by flow cytometry, the role of syndecan-1 expressed by SLE patient pDCs in IFN expression, and the role of patient serum in syndecan-1 surface expression on pDCs.

The purpose of this study is to evaluate the safety and efficacy of oral Pyridorin 300 mg BID in reducing the rate of progression of nephropathy due to type 2 diabetes mellitus.

The purpose of this study is to determine the effectiveness, durability, and long-term safety of Reloxaliase in patients with Enteric Hyperoxaluria.

This study aims to understand the pharmacogenomics of Native American patients compared to Caucasians who are undergoing kidney transplant for treatment of kidney disease.

Evaluate the efficacy and safety of ALLN-177 in reducing plasma and urinary oxalate levels in adult and pediatric patients with enteric hyperoxaluria and hyperoxalemia or primary hyperoxaluria.

American Indians (AI) have cultural, emotional, physical and religious variables that influence the patient’s perception about kidney transplantation and dialysis, some of which may lead to delays in completion of kidney transplant evaluation and kidney transplantation. The purpose of this study is to asses the patient's perceptions about the kidney transplant evaluation process at Mayo Clinic Arizona, assess the patient's attitudes and feelings about the process of kidney transplantation and how that influences their emotional, physical, cultural and religious well-being and determine the patient's attitude and experience with their dialysis.