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  • A Biobank for Functional Gastrointestinal Disorders (FGID) Rochester, Minn.

    The purpose of this study is to develop a resource (bank) of biospecimens and data collected from individuals with functional gastrointestinal disorders (FGID) to facilitate discovery and development of novel microbial biomarkers of disease and response to treatment, and novel targeted therapeutic strategies for FGID.  

  • Effects of Gum Arabic on Gastrointestinal Transit and Permeability Rochester, Minn.

    This study is being done to determine if a low-dose or high-dose prebiotic along with a high-fiber diet improves symptoms of diverticulitis and gut function

  • Role of Gut Microbiome in Cancer Therapy Jacksonville, Fla., Rochester, Minn., Scottsdale/Phoenix, Ariz.

    The purpose of this study is to correlate gut microbiome with specific cancer diagnoses and the clinical response (effectiveness), and adverse effects of cancer therapy (single or multiple) and stem cell transplant.

     

  • The Characteristics and Role of Mucosal Microbiome after Treatment of Clostridium-difficile Infection Rochester, Minn.

    The purpose of this study is to characterize the mucosal microbiome in patients who have recently been treated for Clostridium-difficile Infection (CDI) in comparison to that of control population to determine the effect of the mucosal associated microbiome on outcome of CDI.

     

  • The Influence of Diet on Host Physiology and Disease Across Diverse Human Gut Microbiotas Rochester, Minn.

    The purpose of this study is to understand the potential of protein and psyllium fiber to manipulate gut microbial densities, intestinal permeability, and inflammation in humans.

  • The Role of Mucosal Microbiome in Recurrence of Clostridium Difficile Infection Rochester, Minn.

    The microbiome within the gut lumen has been found in prior studies to differ in individuals with C. difficile infection (CDI) in comparison to those without diarrhea. The microbiome associated with the mucosal surface on the colon has been noted to differ from that of the lumen in other clinical scenarios, although this has not been studied in depth in patients with CDI. The goal of this research is to characterize the mucosal microbiome in patients with CDI after treatment to characterize this microbiome and determine the effect on recurrence of CDI.

  • The Role of Mucosal Microbiome in the Development, Clearance and Recurrence of Clostridium Difficile Infection Rochester, Minn.

    The purpose of this study is to characterize mucosal and luminal microbiome in patients diagnosed with Clostridium difficile infection (CDI), at the time of diagnosis and after treatment, to determine the effect of mucosa associated microbiome on outcome of CDI and the effect of antibiotic treatment on mucosa associated microbiome

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