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  • A Multicenter Trial of a Shared Decision Support Intervention for Patients and Their Caregivers Offered Destination Therapy for End-Stage Heart Failure (DECIDE-LVAD) Rochester, Minn.

    The purpose of this study is to evaluate the effectiveness and implementation of a new shared decision support tool. Using feedback from patients, caregivers, and clinicians, a paper and video decision aid has been made to help people who are offered DT LVAD (a partial artificial heart—so-called destination therapy left ventricular assist device) make this most difficult of decisions. Although patients may live longer with a DT LVAD, it poses many risks, including stroke, serious infection, and bleeding.Unlike the information that is now available, our decision aid focuses on options, fears, and the needs of caregivers, is balanced, and is paired with training for doctors and nurses on how to best talk about DT LVAD.

     

  • Caregivers of Patients with Heart Failure Rochester, Minn.

    The purpose of this study is to identify the burden, benefits, or impact of caregiving on the health of the caregiver and patient with heart failure.

  • Predictors of Healthcare Resource Utilization in Patients with Heart Failure Rochester, Minn.

    We will longitudinally (at enrollment and 6 months after) ascertain patients’ end of life preferences, patient activation and health literacy in prospectively enrolled Southeastern Minnesota residents hospitalized with heart failure (HF). 

    We will define the relationship between HF patients’ end of life preferences and degree of advance care planning and healthcare resource utilization. 

    We will measure perceived treatment burden in patients hospitalized with heart failure using a novel questionnaire that has been validated in patients with multimorbidity. 

  • PROVIDE-HF: Patient Reported Outcomes inVestigation Following Initiation of Drug Therapy With Entresto (Sacubitril/Valsartan) in Heart Failure (PROVIDE-HF) Rochester, Minn.

    Real-world evidence of the clinical course of patient symptoms following initiation of sacubitril/valsartan via PROs with a patient-centered study design will provide important evidence of potentially beneficial outcomes associated with the use of this therapy.

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