Outcomes of Perioperative Vision Loss
The goal of this study is to update the incidence of perioperative vision loss from ischemic optic neuropathy, retinal vein or artery occlusion, and cortical blindness from all non-ocular general anesthesia surgery, including robotic surgery, that has been performed at Mayo Clinic from 2003-2012. The study will also aim to determine the visual acuity outcomes following perioperative vision loss.
A Study to Evaluate the Effectiveness and Safety of Brolucizumab vs. Aflibercept in Patients with Visual Impairment Due to Diabetic Macular Edema
The purpose of this study is to evaluate the effectiveness and safety of brolucizumab vs. aflibercept in the treatment of patients with visual impairment due to diabetic macular edema (DME).
New Enrollment Post-Approval Study of the Argus® II Retinal Prosthesis System
This post-approval study is being implemented to monitor the use of Argus II System in a larger US population than available within pre-approval studies. An attempt will be made to include all eligible and willing subjects implanted with Argus II System in the United States.
Developing Criteria for Treatment of Neurofibromatosis Type 1 Associated Optic Pathway Glioma
The purpose of this research study is to understand the natural history of vision in patients with OPG and determine if there are factors (e.g. age at diagnosis, male/female, tumor location, features of the MRI exam, etc) that predict future vision loss or change in tumor size.
Another purpose of the study is to collect and store blood and tissue samples to use for future research to evaluate if there are certain variations in DNA, RNA, or proteins that predict the likelihood of an OPG to grow or cause vision loss.