Clinical Trials

The purpose of this study is to demonstrate the technical feasibility of the Saline-Enhance Radiofrequency (SERF) Catheter and SERF Cardiac Ablation System to eliminate or control ventricular tachycardia (VT).

The purpose of this study is to demonstrate that scar-based ventricular tachycardia (VT) ablation using the FlexAbility™ ablation catheter system results in a superior clinical outcome compared to routine drug therapy in subjects with documented Monomorphic Ventricular Tachycardia [MMVT] (both ischemic and non-ischemic) while maintaining an acceptable safety profile.

The purpose of this study is to measure the effect on ventricular ectopy, safety, tolerability and pharmacokinetics of S48168 (ARM210) compared with placebo in participants with Type 1 Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT1).

The purpose of this study is to compare the safety and effectiveness of Edoxaban to Warfarin when used in patients with a non-valve related atrial fibrillation undergoing clinically indicated implantation or replacement of cardiovascular implantable electrical devices.

The purpose of this study is to determine if nonInvasive cardiac radioablation (NICRA) can provide selective access to deeper scarred myocardial tissue for ablation. 

The purpose of this study is to compare the rate of arrhythmia-induced events between paediatric Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) patients with and without implantable cardioverter defibrillator (ICDs), and to determine the quality of life and psychosocial functioning of paediatric CPVT patients with and without ICDs.

The purpose of this study is to demonstrate the safety and effectiveness of ventricular ablation therapy using the FlexAbility Sensor Enabled Ablation Catheter in patients with drug-refractory monomorphic ventricular tachycardia in whom ventricular tachycardia recurs despite antiarrhythmic drug therapy or when antiarrhythmic drugs are not tolerated or desired.

The purpose of this study is to determine if common genetic variants that underlie the QT interval are also associated with medication-induced torsade de pointes (TdP).

The aim of this study is to determine the outcomes of catheter ablation before transcatheter PVR among patients with Tetralogy of Fallot (TOF, a specific type of congenital heart defect). It is hypothesized that a combination of successful catheter ablation and transcatheter PVR placement will result in a reduction in a conventional risk score calculation (and consequently, fewer patients meeting criteria for primary prevention ICD placement) owing to a combination of VT circuit elimination and favorable RV remodeling.

The purpose of the MODULAR ATP Clinical Study is to demonstrate safety, performance, and effectiveness of the Modular Cardiac Rhythm Management (mCRM) Therapy System.

The purpose of this study is to evaluate the feasibility and safety of a management approach that incorporates VT-ablation and S-ICD implantation in secondary prevention patients. This is a single arm prospective study with 30 patients eligible for implantation of an ICD for the secondary prevention of sudden cardiac death.

The purpose of this study is to identify and characterize heart rhythm disorders including atrial arrhythmias such as atrial fibrillation, ventricular arrhythmias such as ventricular tachycardia, conduction abnormalities, etc. among patients with spontaneous coronary artery dissection (SCAD).