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TRITON-PN: A Study To Evaluate The Efficacy And Safety Of Nucresiran In Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy
Rochester, MN
The purpose of this study is to:
* Determine the efficacy of nucresiran in patients with hATTR-PN by evaluating the effect on neurologic impairment, quality of life, nutritional status, disability, and gait speed
* Demonstrate superiority of nucresiran compared to in-study vutrisiran with respect to serum transthyretin (TTR) levels
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A Non-interventional Cohort Safety Study Of Patients With HATTR-PN
Rochester, MN
The purpose of this study with the Health Authorities from the United States (US), Canada and Europe, is to collect long-term safety information (including any potential side effects) for the drug TEGSEDI in patients with hATTR-PN under real-world conditions.
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A Study To Evaluate The Efficacy And Safety Of AKCEA-TTR-LRx In Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
Scottsdale/Phoenix, AZ
The purpose of this study is to evaluate the effectiveness and safety of AKCEA-TTR-LRx after administration for 65 weeks to patients with hereditary transthyretin-mediated amyloid polyneuropathy (hATTR-PN), as compared to the NEURO-TTR trial (NCT01737398).
For more information, please visit http://www.neuro-ttransform.com/.