Clinical Trials

Patent ductus arteriosus (PDA)

Displaying 2 studies

Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus Rochester, MN

The primary goal of the trial is to compare two different Patent Ductus Arteriosus (PDA) treatment approaches: 1) an "early treatment" approach or 2) a "conservative" approach. For the purposes of the study infants will be enrolled if they are delivered before 28 weeks gestation and have a moderate/large PDA present at 5-7 days after birth.

The hypothesis is: treatment of a moderate size patent ductus arteriosus (PDA) will decrease the time needed for assisted respiratory support, diuretic therapy, and gavage feeding assistance, in addition to decreasing the incidence of ductus ligations or need for future outpatient cardiology follow-up appointments. The ...
Determining the Natural and "Unnatural" History of Anomalous Aortic Origin of a Coronary Artery with an Interarterial or Intraconal or Intermural Course (AAOCA): Establishing a Multi-Institutional Registry Rochester, MN

The purpose of the study is to determine the outcome of surgical intervention versus observation in children and young adults with AAOCA. To do this the plan is to create a registry of AAOCA subjects that will enable us to develop a risk stratification model utilizing a large multi-institutional registry under the auspices of the Congenital Heart Surgeons’ Society (CHSS).