Clinical Trials

NF2-related schwannomatosis (neurofibromatosis type 2)

Displaying 2 studies

  • Efficacy And Safety Of REC-2282 In Participants With Progressive NF2 Mutated Meningiomas (POPLAR-NF2) Rochester, MN

    The purpose of this study is to investigate the effectiveness and safety of REC-2282 in patients with progressive NF2 mutated meningiomas who have either NF2 disease-related meningioma or sporadic meningiomas that have NF2 mutations.

  • Innovative Trial For Understanding The Impact Of Targeted Therapies In NF2 Rochester, MN

    The purpose of this study is to test multiple experimental therapies simultaneously in patients with neurofibromatosis type 2 (NF2) with associated progressive tumors of vestibular schwannomas (VS), non-vestibular schwannomas (non-VS), meningiomas, and ependymomas. This Master Study is being conducted as a "basket" study that may allow people with multiple tumor types associated with NF2 to receive new drugs throughout this study. Embedded within the Master Study are individual drug substudies. - Investigational Drug Sub-study A: Brigatinib.

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