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A Study of Environmental Risk Factors for the Anti-Synthetase Syndrome
No Locations
Like other complex diseases, autoimmune diseases are the result of numerous causes, including genetic and environmental factors. Some researchers believe that people who are susceptible to autoimmune disorders develop them when the body reacts to environmental or other factors by creating white blood cells that attack the body s own tissues, which then progresses to autoimmune diseases. These immune-triggered disorders can overlap with one another to some extent, but most autoimmune diseases have certain distinct triggers. - The autoimmune disorder myositis weakens the muscles and may cause other health problems. Environmental exposures associated with myositis include ultraviolet radiation, stressful life ...
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A Study to Evaluate Electrical Impedance Myography as an Outcome Measure in Myositis
Jacksonville, FL
The purpose of this study is to assess Electrical Impedance Myography (EIM) as an outcome measure in patients with Idiiopathic Inflammatory Myopathies (IIM) or Myositis.
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A Study To Determine The Efficacy And Safety Of ABC008 For Inclusion Body Myositis
Jacksonville, FL; Rochester, MN
The purpose of this study is to determine the effectiveness, safety, and tolerability of subcutaneous (SC) dosing of ABC008 in subjects with inclusion body myositis (IBM).
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Long-term Extension Study Of Ulviprubart (ABC008) In Subjects With Inclusion Body Myositis
Jacksonville, FL; Rochester, MN
ABC008-IBM-202 is an open-label, multicenter study to evaluate the safety and efficacy of long-term administration of ulviprubart (ABC008) in subjects with IBM who have completed either Study ABC008-IBM-101 or Study ABC008-IBM-201. Subjects may be enrolled in this study if they meet study eligibility criteria and:
* Have completed the Part 2 (Multiple Ascending Dose \[MAD\]) End of-Treatment (EOT) Visit in Study ABC008-IBM-101; subjects who continued further on into Part 3 of the study (MAD Extension) prior to enrolling in this study are also eligible; OR
* Have completed the Week 80 Follow-up Visit in Study ABC008-IBM-201.
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Gene Analysis in Families with Probable Inclusion Body Myositis with or without and ALS
Rochester, MN
This study proposes to identify the molecular defect in families with a clinical phenotype of “probable Inclusion Body Myositis” (“probable IBM”) but affecting more than one family members, with or without family history of ALS.
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Immunological Consequences of COVID-19 Vaccination in Patients with Rheumatic Diseases
Rochester, MN
This research trial will study the immune respone to COVID-19 vaccination in patients with rheumatic diseases.