Metabolic liver disease

Displaying 3 studies

  • A Study to Evaluate Non-invasive Biomarkers of Metabolic Liver Disease Rochester, MN

    The purpose of this study is to assess the repeatability and reproducibility of a set of specified MRI quantitative biomarkers.  The imaging biomarkers will cover an array of methods that could be applicable to non-alcoholic fatty liver disease (NAFLD), including liver fat, liver stiffness, corrected T1 relaxation time and body composition assessments. The data collected will be used to inform a decision of which of these biomarkers has sufficient precision to be advanced to NIMBLE Stage 2.

    NIMBLE is a comprehensive, five-year collaborative effort to standardize, compare, validate, and advance the regulatory qualification of imaging and circulating biomarkers to diagnose and stage nonalcoholic ...

  • Primary Cell Lines Derived from the Human Gall Bladder for the Purpose of Gene and Cell Therapy for Metabolic Liver Disorders Rochester, MN

    This research study will help us to improve our understanding of normal liver and gallbladder function. Additionally, this research study will be used to try to discover new therapies for treating liver disease using gallbladder cells.

  • Biobank for Cholestatic Liver Diseases Rochester, MN

    This study is a biobank of specimens and clinical data for use in current and future research to better understand the cholestatic liver diseases primary biliary cirrhosis/cholangitis (PBC) and primary sclerosing cholangitis (PSC).


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