Clinical Trials

Lymphatic malformation

Displaying 3 studies

Study Evaluating The Safety And Efficacy Of PTX-022 (QTORIN Sirolimus) In The Treatment Of Microcystic Lymphatic Malformations Rochester, MN

The purpose of this research is to see if a new topical (applied to the skin) formulation of sirolimus, PTX-022, is safe and effective in treating people with microcystic Lymphatic Malformations (mLM).
A Phase 2, Baseline-Controlled Study Evaluating The Safety And Efficacy Of PTX-022 (Sirolimus) Topical Gel 3.9% In The Treatment Of Cutaneous Venous Malformations Rochester, MN

The purpose of this study is to evaluate the safety and efficacy of PTX022 (sirolimus) Topical Gel 3.9% in the Treatment of Cutaneous Venous Malformations.
RLY-2608-201-Ph2 Study Of RLY-2608 In PROS And PIK3CA Driven Malformations Rochester, MN

The purpose of this study is to compare the efficacy and safety of RLY-2608 versus placebo in adult, adolescent, and pediatric participants with PROS and malformations driven by PIK3CA mutations, which is preceded by a dose selection and basket design with exploratory single-arm cohorts for various subpopulations of participants.