-
DNA and RNA Testing in Patients With Hereditary Cancer Syndromes
Rochester, MN
The purpose of this study is to evaluate the performance characteristics of RNA sequencing. To investigate the utility of RNA analysis in diagnosis of patients with cancer predisposition syndromes and collection of patient samples with pathogenic or likely pathogenic variants in hereditary cancer predisposition genes (i.e., collection of positive controls) is required for above studies.
-
Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome
Scottsdale/Phoenix, AZ; Rochester, MN
The purpose of this study is to evaluate if the combination of trivalent adenovirus-5 (Tri-Ad5) vaccines and IL-15 superagonist N-803 reduces the incidence of colorectal neoplasms in patients with Lynch syndrome (LS).
-
A Study of the Quality of Life of Patients who have Hereditary Nonpolyposis Colorectal Cancer
Rochester, MN
The purpose of this study is to show the quality of life and bowel function in patients who have been diagnosed with rectal cancer and are known to have Hereditary Nonpolyposis Colorectal Cancer (HNPCC), especially to make comparisons between clinical managements, family history, and health behaviors.