Gender dysphoria

Displaying 6 studies

  • A Study to Assess Kidney Function Markers in Transgender Individuals Receiving Gender-affirming Hormone Therapy Rochester, MN

    The purpose of this study is to determine how cystatin C, creatinine, and microalbuminuira change with gender affirming hormone therapy initiation. Blood draws and urine testing will be done at time 0, 3 months, and 6 months of hormone therapy. The results will  determine how to best interpret lab values in transgender individuals receiving gender affirming hormone therapy.

  • A Study to Assess Transgender Volumetric Bone Density in Cross Sex Hormone Therapy Rochester, MN

    The purpose of this study is to monitor short term changes in bone microarchitecture, with the initiation of cross sex hormone therapy in transgender men and transgender women – during this time, there is a large flux in hormonal status.

  • A Study of Trans Sexualities Rochester, MN

    The purpose of this study is to qualitatively examine and describe the ways in which trans people experience sexuality (desire, eroticism), and to explore how trans individuals describe the connections between gender and sexuality.


  • A Study to Analyze Gender Congruence After Gender Confirmation Surgery Rochester, MN

    The purpose of this study is to assess the success and effectiveness of gender confirmation surgeries on eliminating gender incongruence and improving life satisfaction, and compare patient’s status with the preoperative results.

  • A Study to Evaluate The Effect of Transgender Hormone Therapy on Adipose Tissue Biology and Distribution Rochester, MN

    The purpose of this study is to determine if cardiometabolic risk correlates with the estradiol (E) to testosterone (T) ratio or circulating concentrations, cross sex hormone duration or route, and to determine if changes in the E/T ratio are associated with changes in insulin sensitivity, body composition and adipose tissue fatty acid metabolism in transgender women.

  • A Study of Cardiovascular Risk Factors in Transgender Children and Youth Rochester, MN

    The purpose of this study is:

    • Specific Aim 1:  To determine the prevalence of obesity, cardiometabolic risk factors and mental health diagnoses among transgender children and adolescents evaluated at the Mayo clinic Transgender and Intersex Specialty Care Clinic (TISCC)
    • Specific Aim 2:  To measure adipokines related to energy homeostasis and insulin sensitivity in transgender children and adolescents and compare with those in cisgender age and gender matched controls.


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