-
A Study of Cerebrospinal Fluid Proteomic, Metabolomic, and Cytokine Profiles in the Central Nervous System
Scottsdale/Phoenix, AZ
The purpose of this study is to examine paired serum and cerebrospinal fluid (CSF) samples from subjects with encephalitis, meningitis, and myelitis to investigate two (2) specific pathways suspected of playing a role in the host response to infection and/or inflammation.
-
Feasibility Of Intraoperative Microdialysis During Neurosurgery For Central Nervous System Malignancies
Rochester, MN
This clinical trial evaluates the use of microdialysis catheters during surgery to collect biomarkers, and studies the feasibility of intraoperative microdialysis during neurosurgery for central nervous system malignancies. A biomarker is a measurable indicator of the severity or presence of disease state. Information collected in this study may help doctors to develop new strategies to better diagnose, monitor, and treat brain tumors.
-
E6201 Plus Dabrafenib For The Treatment Of Metastatic Melanoma Central Nervous System Metastases (CNS)
Scottsdale/Phoenix, AZ; Jacksonville, FL; Rochester, MN
The purpose of this study is to determine the overall rate of response of brain metastases in subjects with central nervous system (CNS) metastases due to metastatic melanoma with a BRAF V600 mutation who have relapsed or progressed from initial or systemic disease.
.