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A Study Of Portable Air Filtration And Indoor Environmental Quality On Healthcare Outcomes In A Home Setting

Overview

About this study

The purpose of this study is to assess the influence of IEQ on health status, chronic disease exacerbations, and symptoms in patients with severe conditions that require care but are manageable from home. In addition, we will assess the potential benefit of the use of portable automated air filtration (the WellCube Air+), which can sense poor air quality (i.e., particulate matter less than 2.5 microns in diameter, PM2.5, levels) and turn on automatically to improve indoor air quality, on these outcome variables as well.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria: 

  • Current HF (class II or class III) patient, or current COPD patient receiving care at home.

  • Currently being treated with the standard of care for their chronic condition.

  • Expected to be stable enough to receive care at home throughout the study timeframe (one month).

  • Interested and willing to participate in the study.

  • Can understand the study needs and complete the consent form.

  • Wi-Fi access within the home.

  • Ability to complete weekly electronic health status surveys on a tablet.

Exclusion Criteria:

  • Does not meet one of the two selected chronic diseases.

  • Is receiving an experimental treatment for their chronic condition.

  • Is not expected to be stable enough to receive clinical care at home throughout the study timeframe (one month).

  • Not interested or willing to participate in the study.

  • Inability to understand the study needs and complete the consent form.

  • Current chronic condition exacerbation requiring in-hospital care.

  • No Wi-Fi access within the home.

  • Inability to complete weekly electronic health status surveys on a tablet.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 09/01/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Contact us for the latest status

Contact information:

Briana Ziegler

5072557125

ziegler.briana@mayo.edu

More information

Publications

Publications are currently not available

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CLS-20611955

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