Clinical Trials

Inclusion Criteria:

• Adult patients (>18 years of age)

• Followed in the outpatient palliative clinic for advanced illness associated pain, nausea, insomnia, depression, or anxiety who report target symptom score > 4 (0-10 Likert Scale). 

• Able to read and write in English

• Access to the online patient portal messaging system.

• Able to apply pressure to auricular devices as instructed.

Exclusion Criteria:

• Delirium, skin disease/sores affecting the ear resulting in inability to apply the acupressure device.

• Received acupuncture or acupressure within the preceding seven days.

• Planned MRI, planned direct radiation to the head, face or ears, or if patient is scheduled for head or neck imaging during the study period. Patients may enroll at a later date when these conflicts no longer exist.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 07/01/2026. Questions regarding updates should be directed to the study team contact.