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A Study Of Urinary Proteomic Before And After Holmium Laser Enucleation Of The Prostate (HoLEP)

Overview

About this study

The purpose of this study is to characterize changes in urinary proteomic signatures before and after HoLEP in men undergoing surgical treatment for benign prostatic hyperplasia (BPH).

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age 18 years or older

  • Scheduled to undergo HoLEP for BPH/bladder outlet obstruction

  • Able to provide informed consent

  • Willing to provide serial urine samples

  • Expected availability for local follow-up in Phoenix area

 

Exclusion Criteria: 

  • Inability to provide informed consent

  • Inability or unwillingness to complete study procedures

  • Inability to provide urine specimens

  • Investigator determination that participation is not feasible or appropriate

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 05/07/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Mitchell Humphreys, M.D.

Contact us for the latest status

Contact information:

Clinical Studies Unit - Arizona

(480) 301-8000

ARZCSUADMIN@mayo.edu

More information

Publications

Publications are currently not available

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CLS-20611430

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