Clinical Trials

Key Inclusion Criteria:

• Adult patients aged 18 years or older.

• Post-orthotopic liver transplant recipient at Mayo Clinic Arizona.

• Able to provide electronic informed consent.

• English proficiency sufficient to provide a 100-300 word natural language sample.

• Consent for language sampling, RUO AlloSure-Liver testing, alcohol biomarker data collection, medication adherence data collection, and EHR outcome analysis.

Key Exclusion Criteria:

• Dual-organ or multi-organ transplant recipients, unless Mayo and CareDx approve inclusion for non-AlloSure analyses in a future amendment.

• Previous allogeneic bone marrow transplant recipient.

• Pregnant patients or patients who become pregnant following liver transplantation, unless Mayo determines that continued data collection is appropriate and permitted.

• Severe cognitive impairment that prevents informed consent or meaningful participation in language sampling.

• Non-fluent English speaker.

• Unwilling to participate or unwilling to permit required data collection and sharing.

• Any Mayo Clinic Arizona transplant exclusion criterion that makes participation inappropriate in the judgment of the clinical team.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 06/16/2026. Questions regarding updates should be directed to the study team contact.