Clinical Trials

Inclusion Criteria:

• Signed informed consent form.

• Diagnosis of indolent systemic mastocytosis as defined by the World Health Organization 2022 criteria.

• Adults ≥ 18 years of age or older.

• Doses of baseline treatment medications are stable for ≥ 14 days prior to enrollment.

• Patient must have an Eastern Cooperative Oncology Group Performance Status of 0 to 2.

Exclusion Criteria:

• Age <18 years old.

• Diagnosis of advanced systemic mastocytosis defined by established criteria as outlined by the World Health Organization 2022 criteria.

• Patient must not have had any cytoreductive therapy including but not limited to cladribine, interferon alpha, pegylated interferon, or antibody therapy < 28 days prior to enrollment.

• Any other significant medical issue as determined by the principal investigator.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 04/20/2026. Questions regarding updates should be directed to the study team contact.