A Study Of Gastric Volume Assessment In Laboring Women With An Epidural After Standardized Beverage

Overview

About this study

The purpose of this study is to assess the gastric volume in laboring parturients with epidural analgesia using gastric ultrasound at 2 hours after consumption of a standardized beverage containing either predominantly fat, protein or carbohydrates.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Female in labor

  • Singleton pregnancy >= 34 weeks

  • Willing to participate

  • Preferred language = English

  • Epidural labor analgesia

  • Empty stomach at time of initial baseline ultrasound assessment or upon re-assessment within 4 hours

Exclusion Criteria:

  • Refusal to participate

  • < 18 years of age

  • Obstetrical contraindication to positioning

  • Uncontrolled pain (non-functioning epidural)

  • Multiple gestation

  • Greater than or equal to 6 cm of cervical dilation at the time of enrollment

  • Prior cesarean or vaginal delivery

  • History of upper GI or gastric surgery

  • History of recent meperidine or metoclopramide use

  • History of diabetes (type 1, type 2, and gestational)

  • History of gastroparesis

  • Morbid Obesity cutoff of BMI > 50

  • Lactose intolerance

  • ASA Class III or greater

  • Active nausea and vomiting in the peripartum period after epidural placement.

  • Inability to consume the total volume of the assigned beverage within 15 minutes

  • Inability to image stomach

  • Chronic opioid consumption > 30mg morphine equivalents per day prior to labor

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 04/15/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Mark Rollins, M.D., Ph.D.

Contact us for the latest status

More information

Publications

Publications are currently not available
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CLS-20603355

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