Clinical Trials

Inclusion Criteria:

• Ability to understand the study procedures and voluntarily provide written informed consent.

• Males and females between age of 18 and 65 years at the time of enrollment.

Exclusion Criteria:

• Active psychiatric disease (i.e., severe depression, severe anxiety disorders, schizophrenia, schizoaffective disorder, bipolar disorder, or post-traumatic stress disorder)

• Active substance use disorder (i.e., current diagnosis of alcohol or substance use disorder, including but not limited to cocaine, amphetamines or methamphetamine, heroin or prescription opioids, or other illicit substances)

• Contraindications to MRI

  • Presence of non-removable MRI-incompatible implants/devices

  • Severe claustrophobia

  • Body weight >300 kg (weight restriction of the MRI scanner)

  • Patients with advanced cervical or thoracic kyphosis

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 04/20/2026. Questions regarding updates should be directed to the study team contact.