Adults With Acute Infection

Overview

About this study

The overall objective of this observational study is to characterize epidemiological, clinical, and biological features of adult patients hospitalized with acute infectious diseases. The study may include respiratory infections, infections outside the respiratory tract, established infectious diseases, and emerging infectious diseases. The specific infectious disease and specific population being studied may vary over time and will be defined in study-specific appendices.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age ≥18 years old.
Admitted to hospital (or in an emergency department with anticipated hospital admission) for the management of a suspected or confirmed acute infectious disease.
Onset of symptoms of an infectious disease within the past 30 days.
Informed consent for study participation by the participant or a surrogate decision maker if the participant lacks capacity for consent.

Exclusion Criteria:

Current imprisonment (this does not include quarantine for an infectious disease).
Patient undergoing comfort care measures only such that treatment focuses on endof-life symptom management over prolongation of life.
Expected inability or unwillingness to participate in study procedures.
In the opinion of the investigator, participation in the study is not in the best interest of the patient.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 4/08/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Zelalem Temesgen, M.D.	Open for enrollment	Contact information: Department of Medicine (DOM) Research Hub (507) 266-1944 DOMRESEARCHHUB@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Zelalem Temesgen, M.D.

Open for enrollment

Contact information:

Department of Medicine (DOM) Research Hub

(507) 266-1944

DOMRESEARCHHUB@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials