Clinical Trials

Inclusion Criteria (All Subjects):

• Age 18 years or older

• Able to provide informed consent

• Fluent in English

Inclusion Criteria (Decompensated Cirrhosis Groups):

• History of cirrhosis, as diagnosed by imaging, elastography, or biopsy

• Evidence of cirrhosis decompensation: history of ascites, variceal bleeding, or development of hepatic encephalopathy

Exclusion Criteria (All Subjects):

• Neurodegenerative disorder (other than hepatic encephalopathy) including Alzheimer’s disease and dementia

• Prior stroke or TIA

• Inability to complete study activities: significant vision/hearing impairments, no access to compatible device for home app use, or other limitation

 Exclusion Criteria (Healthy Control Group):

• History of cirrhosis, as diagnosed by imaging, elastography, or biopsy

• Serious ongoing chronic condition

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 02/02/2026. Questions regarding updates should be directed to the study team contact.