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A Study Of CRC Using Breath And Urine Analysis

Overview

About this study

The purpose of this study is to to develop a non-invasive diagnostic platform for colorectal cancer (CRC) detection using volatile organic compounds (VOCs) found in exhaled breath.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age 45–85 years

  • Confirmed diagnosis of CRC (for case group) or recent negative colonoscopy (for control group)

  • Willingness to provide breath and urine samples.

  • Ability to provide informed consent.

Exclusion Criteria:

  • Active respiratory disease (e.g., COPD, asthma exacerbation)

  • Recent antibiotic use (within 30 days)

  • Recent surgery or chemotherapy (within 3 months)

  • Active tobacco, alcohol, or illicit drug use.

  • Pregnancy

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 6/05/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Contact us for the latest status

Contact information:

Clinical Studies Unit

(904) 953-2255

More information

Publications

Publications are currently not available

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CLS-20598649

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