A Study Of Sorbitol Dehydrogenase (SORD) Deficiency

Overview

About this study

The purpose of this study is to develop clinical assays, both biochemical and molecular, for SORD deficiency and other metabolic conditions in the Biochemical Genetics Laboratory (BGL) using specimens collected from consenting individuals who have a confirmed diagnosis of SORD or other inborn error of metabolism disease (IEM), are a first degree relative of an individual with an IEM, or have another condition that causes a metabolic disturbance.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • For individuals with a known diagnosis to be included, previous biochemical or molecular genetic testing must confirm their diagnosis.  For relatives to be included they must be first degree relatives.

 

Exclusion Criteria: 

  • Individuals that do not meet the above inclusion criteria.   

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

 

Eligibility last updated 07/01/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Matthew Schultz, Ph.D.

Contact us for the latest status

Contact information:

RST Biochemical Genetics Laboratory Genetic Counselor

(507) 266-4996

BIOCHEMICALgenetics@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20598495

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