A Study Of Noninvasive Imaging Predictors Of Tumor Aggressiveness In Renal Masses

Overview

About this study

The purpose of this study is to link physiological mpMRI metrics of tumor blood flow, lipid content, cellularity, and metabolic alterations to tumor aggressiveness in SRMs.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patient with known or suspected renal mass and scheduled for clinical nephrectomy (partial or radical)

  • Age ≥ 18 years

  • Women of child-bearing potential must agree to undergo a urine pregnancy screening per standard Radiology departmental protocol in place, to prevent imaging of pregnant patients. A female of child-bearing potential is any woman (regardless of sexual orientation, having undergone a tubal ligation, or remaining celibate by choice) who meets the following criteria: has not undergone a hysterectomy or bilateral oophorectomy; or has not been naturally postmenopausal for at least 12 consecutive months (i.e., has had menses at any time in the preceding 12 consecutive months)

  • Ability to understand and the willingness to sign a written informed consent.

Exclusion Criteria: 

  • Unable to undergo an MRI (e.g. indwelling device, severe claustrophobia)

  • History of allergic reactions to gadolinium-based contrast agents. Patient may still be enrolled and undergo the non-contrast portion of the MRI study.

  • Subjects must not be pregnant.

  • Unable to sign informed consent.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/02/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Durga Udayakumar

Open for enrollment

Contact information:

Ryan Jacobson

(507) 538-8024

jacobson.ryan1@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20597339

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