A Study Of MME For MMPRTs

Overview

About this study

The primary research objective is to assess whether concomitant centralization in medial meniscus root repair following medial meniscus posterior root tears in adults aged 18 to 65 is associated with decreased meniscal extrusion on postoperative magnetic resonance imaging (MRI).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults aged 18 to 65 (men or women)

  • Type 2 Medial Meniscus Posterior Root Tear demonstrated on MRI.

  • Notable extrusion (>3 mm) on preoperative MRI.

  • Patient able to consent for themselves.

  • Patient agrees to comply with trial schedules and plan

Pre-operative Exclusion:

  • Concomitant ligamentous or meniscal procedures.

  • Meniscal extrusion > 6 mm on pre-operative MRI.

  • Kellgren-Lawrence grade > 2.

  • Varus Malalignment > 5 degrees.

  • Previous surgery of the affected knee.

  • Associated fractures requiring surgery.

  • Concurrent Vascular injuries.

  • Hypermobility/Ehlers-Danlos Syndrome.

  • Inflammatory or autoimmune disease.

  • Severe mental/physical disability precluding post operative rehabilitation demands

  • Contraindications to MRI.

Arthroscopy Inclusion Criteria:

  • Complete radial tears within 9 mm of medial meniscus posterior root.

  • ICRS Grade 3 or better.

Arthroscopy Exclusion Criteria:

  • Requiring concomitant procedures other than MMPRT.

  • ICRS Grade 4 changes.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/03/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Aaron Krych, M.D.

Open for enrollment

Contact information:

Sejal Dave

(507) 266-9085

dave.sejal@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20595848

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