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Polyethylene Wear Particle Analysis of Total Hip Arthroplasty

Overview

About this study

The purpose of this study is to investigate whether a newly introduced polyethylene (highly cross-linked polyethylene, vitamin E-containing polyethylene in vivo) can suppress wear debris production more than conventional polyethylene. If the newly introduced polyethylene can reduce wear debris production, it is expected to reduce failure of artificial joints in the future. However, if newly introduced polyethylene is actually increasing wear debris production, it could be an early alarm bell for surgeons around the world. In other words, the international and social impact of this research is extremely large.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients undergoing revision hip arthroplasty within the study period.
  • Patients over 20 years old.
  • Patients who have received a sufficient explanation, have sufficient understanding, and have given their free written consent.
  • Patients who have passed 2 years or more since their first total hip arthroplasty.

Exclusion Criteria: 

  • Patients who are judged to be unsuitable as research subjects by the research physician.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 5/09/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Nicholas Bedard, M.D.

Open for enrollment

Contact information:

Laura Dohrmann

(507) 266-5886

Beinborn.Laura@mayo.edu

More information

Publications

Publications are currently not available

More about research at Mayo Clinic

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CLS-20595599

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