Clinical Trials

Inclusion Criteria:

• 18 to 70 years of age
• Currently on a typical Western/American diet based on medical records
• No exclusion for nut allergies or any other type of allergies

Exclusion Criteria: 

• Pregnancy or lactation
• Current use of a vegan diet
• BMI ≤ 22, or weight >105 kg (limit of the MRI table)
• Pre-existing significant degree of cardio-pulmonary disease—heart failure with reduced EF of 35 or lower, unstable arrythmia, severe degree of pulmonary hypertension, severe degree of obstructive or restrictive lung disease.
• Currently on or starting any weight loss medications during the 1-month plant- based diet period
• Starting a new exercise regime during the 1-month plant- based diet period
• Patient with contraindications to MRI. These may include the presence of electrically, magnetically, or mechanically activated implants (such as cardiac pacemakers, cochlear implants, implanted pumps), metallic clips in the brain, and inability to follow commands or tolerate MRI. )

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 02/18/2025. Questions regarding updates should be directed to the study team contact.