Clinical Trials

Inclusion Criteria:

• Subject with moderate to severe facial photoaging.
• Female or male subject age 40-99 years.
• Subject with Fitzpatrick skin types I-III.
• Subject has signed an Informed Consent Form in compliance with 21CFR Part 50: "Protection of Human Subjects."
• Subject is dependable and able to follow directions and is willing to comply with the schedule of visits.

Exclusion Criteria:

• Any dermatological disorder, which in the investigator’s opinion, may interfere with the accurate evaluation of the subject's skin characteristics, except for the conditions associated with sensitive skin or photoaging skin.
• Subjects who are pregnant or lactating.
• Subjects with history of hypertrophic scarring or keloids.
• Subjects who do not agree to refrain from direct sun exposure during the study duration.
• Subjects who are unwilling or unable to comply with the requirements of the protocol.
• Subjects with any planned surgeries and/or invasive medical procedures during the study.
• Subjects currently receiving any anticancer, immunosuppressive treatments/ medications (e.g., azathioprine, belimumab, cyclophosphamide, etanercept, adalimumab, mycophenolate mofetil, methotrexate, prednisone, infliximab, ustekinumab), or radiation.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 5/16/2024. Questions regarding updates should be directed to the study team contact.