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Acute Respiratory Effects of Toxic Asphalt Emissions

Overview

About this study

The purpose of this study is to determine the acute influence of inhaling a cocktail of emissions from asphalt on lung physiology with and without a filter ( ASU novel adsorbent) and also to determine if this cocktail has cardiopulmonary effects, such as changes in heart and lung function and brain blood flow. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Healthy adults between the ages of 18-50 years.

Exclusion Criteria:

  • Those with a history of pulmonary, cardiovascular, metabolic disease, neural/cognitive disorders, or are pregnant, if they currently smoke or have had a significant history of smoking (>5 pack yrs.) 

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 08/27/2024. Questions regarding updates should be directed to the study team contact.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Contact us for the latest status

Contact information:

Courtney Wheatley-Guy Ph.D.

(480) 301-6616

Wheatley.Courtney@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Open for enrollment

Contact information:

Courtney Wheatley-Guy Ph.D.

(480) 301-6616

Wheatley.Courtney@mayo.edu

More information

Publications

Publications are currently not available

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