Virtual Reality for Blood Pressure Reduction with Validation Ambulatory Blood Pressure Monitoring (ABPM)

Overview

About this study

The purpose of this study is to evaluate the effectiveness of a calming virtual reality (VR) environment in reducing office blood pressure (OBP) among patients with suspected white coat hypertension (WCH) or white coat effect (WCE). Effectiveness will be assessed by comparing pre- and post-VR OBP measurements. WCH/WCE diagnosis will be confirmed using ambulatory blood pressure monitoring (ABPM).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Citeria:

Adults ≥18 years old undergoing ABPM at the Mayo Clinic in Florida for any clinical indication.
Ability to provide informed consent.

Exclusion Criteria:

History of epilepsy or seizure disorders.
Significant cognitive impairment (e.g., dementia, Alzheimer’s disease) that may interfere with VR engagement.
Significant visual impairment that prevents adequate visualization of the VR environment.
History of vestibular disorders (e.g., Meniere’s disease, chronic vertigo).
Unstable cardiovascular conditions (e.g., recent myocardial infarction within the past year).
Chronic hypoxemic respiratory failure requiring supplemental oxygen therapy by nasal cannula.
Cervical spine instability or injuries that could impair safe VR use.
Pregnancy.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 02/10/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Jacksonville, Fla. Mayo Clinic principal investigator Lyle Baker, M.D.	Open for enrollment	Contact information: Quantia Wilkes M.S. (904) 953-6838 Wilkes.Quantia@mayo.edu

Mayo Clinic Location

Status

Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Lyle Baker, M.D.

Open for enrollment

Contact information:

Quantia Wilkes M.S.

(904) 953-6838

Wilkes.Quantia@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials