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Normative Metrics of Cerebral Autoregulation in Young and Older Adults

Overview

About this study

The purpose of this study is to investigate age-related differences in cerebral autoregulation metrics between young and older adults using transfer function analysis of transcranial doppler ultrasound.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Ages 18 – 80 years, English speaking.

Exclusion Criteria: 

  • Participants with a history of ischemic stroke, hemorrhagic stroke, traumatic brain injury, myocardial infarction, previous major cardiovascular surgeries (stent, CABG, bypass, transplant), previous major neurologic surgeries (lesion resection, deep brain stimulation, bypass, placement of a shunt/drain), or permanent neurologic dysfunction such as spinal cord injury or cerebral palsy.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 4/08/2025. Questions regarding updates should be directed to the study team contact.
 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Open for enrollment

Contact information:

Kevin Webb Ph.D.

(507) 284-7208

Webb.Kevin@mayo.edu

More information

Publications

Publications are currently not available

More about research at Mayo Clinic

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CLS-20583543

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