Treating Epilepsy With Transcranial Direct Current Stimulation


About this study

The purpose of this study is determine the feasibility and efficacy of at-home Transcranial Direct Current Stimulation (tDCS) therapy for focal epilepsy.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

- Clinical diagnosis of focal epilepsy.

- Estimated to have at least 2 countable seizures per month.

- Has not had control with at least 2 anti-seizure medicines.

- Able to maintain a constant medication for duration of the study (rescue meds

- Subject or legally authorized representative is able to understand consent and keep a
seizure diary in English.

Exclusion Criteria:

- A disease likely to progress over course of the study.

- Psychogenic non-epileptic seizures.

- Suicide attempt or psychiatric hospitalization past 2 years.

- A skin condition interfering with scalp electrodes or allergy to silver.

- Women will verify not pregnant, and if applicable, have a serum pregnancy test.

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 3/15/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Brian Lundstrom, M.D., Ph.D.

Open for enrollment

Contact information:

Iesha Abbajebel

(507) 422-9975

More information


Publications are currently not available

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