In Vitro 3D Cell Culture Models Validation For Tumor Drug Sensitivity After Tissue Removal

Overview

About this study

The purpose of this study is to validate that tumor organoid drug sensitivity is representative of patient treatment outcomes.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Provision of signed and dated informed consent form. Patients must consent to giving tissue as well as allowing for their de-identified medical history information regarding administered treatments and treatment outcomes to be shared.
Stated willingness to comply with all study procedures and availability for the duration of the study
Males or females, aged ≥ 18 years.
A demonstrated primary solid cancer for which it is medically indicated and planned to be surgically resected, biopsied, or drained (via malignant pleural effusion).
A target tumor that can provide a tissue sample >1cm3 in size.
The ability to ship the tissue sample within 24 hours of removal from the patient.
Willingness to adhere to the treatment follow-up regimen.

Exclusion Criteria:

Individuals < 18 year of age.
Presence of a condition(s) or diagnosis, either physical or psychological, or physical exam finding that precludes participation in the opinion of the Investigator.

Eligibility last updated 12/15/21. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Janani Reisenauer, M.D.	Closed-enrolling by invitation What is this? (?) "Close" Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.	Contact information: Pulmonary Clinical Research Unit (800) 753-1606 PCRUE18@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Janani Reisenauer, M.D.

Closed-enrolling by invitation

Contact information:

Pulmonary Clinical Research Unit

(800) 753-1606

PCRUE18@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials