Monoclonal Proteins by Blood Spot and Saliva


About this study

The purpose of this study is to assess the feasibility and develop procedures for detecting monoclonal proteins via finger pick blood spots and saliva. Data will be compared to results of serum data collected for patient care during the same time.  The test will be evaluated qualitatively against venipunctured data tested by Mass Fix.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adult patients ≥ 18 years old.
  • Diagnosed with plasma cell disorders.

Exclusion Criteria:

  • Children < 18 years old.
  • Pregnant females.

Eligibility last updated 5/2/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

David Murray, M.D., Ph.D.

Open for enrollment

Contact information:

David Murray M.D., Ph.D.

(507) 293-1321

More information


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