Clinical Evaluation of a Transmit/Receive Head Coil for PET/MR Brain Studies


About this study

The purpose of this study is to evaluate an attenuation map for a transmit/receive (T/R) head coil used on the GE SIGNA PET/MR system. An attenuation map of the T/R head coil will be developed and evaluated in phantom experiments followed by the patient studies. The repeatability of generating patient-specific attenuation maps from Zero Echo Time (ZTE) MR images acquired with the T/R head coil will also be assessed.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • 18 years of age or older.
  • Patients who are able and willing to sign the informed consent.
  • A negative urine pregnancy test within 48 hours prior to PET imaging procedures in females of childbearing potential.
  • Patients who are scheduled and considered eligible (according to MRI safety policies) for a clinically-indicated PET/MR epilepsy or dementia study.

Exclusion Criteria:

  • Individuals < 18 years of age.
  • Patients who are unable to lay still for an additional 15 minutes.

Eligibility last updated 1/26/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Bradley Kemp, Ph.D.

Closed for enrollment

Contact information:

Kurt Kevin Degillo CCRP

(507) 422-5407

More information


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