NIRS - Minimal Risk


About this study

The purpose of this study is to compare measurements of muscle oxygen transport between two different types of NIRS devices (CW-NIRS and FD-NIRS). Specifically, indices of muscle mitochondrial capacity, perfusive and diffusive oxygen conductance during exercise, and muscle microvascular function will be investigated. We will also explore individualized normalization strategies to minimize discrepancies between these technologies.      



Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Healthy adults between the ages of 18 and 45.

Exclusion Criteria:

  • Individuals < 18 or > 45 years of age.
  • Pregnant women (testing will be done by research team if requested).
  • History of pulmonary, neurologic, cardiovascular, or musculoskeletal diseases.

Eligibility last updated 10/26/21. Questions regarding updates should be directed to the study team contact.




Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

Contact information:

Shelly Roberts R.N.

(507) 255-2807

More information


Publications are currently not available

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