Sex Differences in The Objective Assessment of Frailty in Subjects Undergoing Early Outpatient Cardiac Rehabilitation: A Pilot Study


About this study

The overarching aim of this project will be to objectively characterizing the frailty phenotype and to assess the prevalence and sex differences of frailty in outpatient cardiac rehabilitation participants. The current proposal seeks to facilitate identification of vulnerable women and adapt their referral, assessment, intervention plan and goals to individualize exercise prescription and improve overall frailty.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adult 18 years and older.
  • English speaking.
  • Able to provide consent.
  • Has a qualifying indication for cardiac rehabilitation (e.g., Acute coronary syndrome, myocardial infarction, percutaneous coronary intervention, coronary artery bypass grafting, and stable angina, heart valve disease) and able to participate in cardiac rehabilitation.
  • Olmsted County MN residents. 

Exclusion Criteria:

  • Individuals < 18 years of age.
  • Unwilling to provide consent.
  • Unable to participate in cardiac rehab.

Eligibility last updated 8/13/21. Questions regarding updates should be directed to the study team contact.



Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Carmen Terzic, M.D., Ph.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Audry Chacin Suarez M.D.

More information


Publications are currently not available

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