Influence of the Postoperative Tibial Slope on Outcomes after Posterior-stabilized Total Knee Arthroplasty


About this study

Some have suggested that targeting neutral alignment of the knee may improve outcomes after primary total knee arthroplasty (TKA). However, most of the discussion has focused on coronal alignment, with little emphasis on sagittal alignment, particularly tibial slope. The goals of this study were to determine the effect of tibial slope on implant survivorship and clinical outcomes of contemporary posterior-stabilized (PS) TKAs.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Primary TKA done in the period from 2002 to 2017 for knee osteoarthritis.
  • Performed unilaterally.
  • Using 1 of the 3 modern PS implant designs used at our institution.
  • With all-polyethylene patellar component.
  • Neutrally-aligned in the coronal plane (mechanical axis, 0° ± 3°) from postoperative full-length hip-knee-ankle radiographs.

Exclusion Criteria:

  • None.

Eligibility last updated 10/21/21. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Matthew Abdel, M.D.

Open for enrollment

Contact information:

Jessica Stutzman

(507) 266-1227

More information


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