A Study to Evaluate the Use of Platelet-rich Plasma to Treat Erectile Dysfunction


About this study

The purpose of this study is to develop and implement an innovative treatment for erectile dysfunction (ED).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • The patient must have given his informed and signed written consent.
  • The patient is a male.
  • Between 45 and 65 years of age.
  • The patient has ED for longer than 1 year but less than 5 years.
  • The subject has a stable partner for at least 3 months.
  • The patient is PDE5i responsive, meaning he is able to achieve and maintain an erection under the effect of the maximal dosage of PDE5i.
  • IIEF-EF, EHS, SEP 2+3, and GAQ Domain score of 17-20.
  • Mild to moderate vascular erectile dysfunction: PSV > 25 cm/sec.

Exclusion Criteria:

  • The patient is participating in another study that may interfere with the results or conclusions of this study.
  • History of radical prostatectomy or pelvic cancer surgery.
  • Prior history of pelvic malignancies.
  • Prior pelvic radiation therapy.
  • Neurological disease which effects erectile function (spinal cord injury, iatrogenic injury to the pelvic or cavernous nerves).
  • Psychiatric disease which effects erectile function.
  • The patient is taking blood thinners.
  • History of Diabetes Mellitus.
  • History of Coronary Artery Disease.
  • Evidence Based Criteria: Doppler Clinical Exam ( PSV < 25 cm/sec defined criteria for severe erectile dysfunction not likely to respond to approved medical therapies).
  • Biochemical evidence of Hypogonadism (total Testosterone < 300 ng/dL).

Eligibility last updated 11/30/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Gregory Broderick, M.D.

Open for enrollment

Contact information:

Michel Tamayo Perez

(904) 953-8257


More information


Publications are currently not available

Mayo Clinic Footer