A Study to Analyze Gut Microbiota Dysbiosis and Asthma Severity


About this study

The purpose of this study is to compare the gut bacterial and fungal microbiota profiles of patients with poorly-controlled asthma and patients with well-controlled asthma. 



Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults, ≥ 18 years of age.
  • Chronic asthma on maintenance therapy with an inhaled corticosteroid or ICS-LABA.

Exclusion Criteria:

  • Use of oral or IV antibacterials within last 30 days.
  • Current treatment with asthma biologic therapy (mepolizumab, benralizumab, omalizumab, or dupilumab).

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Joseph Skalski, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Shannon Daley C.C.R.C., CCRP

(507) 293-0637


More information


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