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cGMP Dolcanatide Responders

Overview

About this study

The purpose of this study is to explore the level of similarity in pharmacodynamic responses to GUCY2C agonists in organoids prepared from rectal biopsies from all healthy subjects, independent of changes in their bowel movements induced by oral administration of 27 mg/day of dolcanatide for 7 days.

 

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Males and females, ≥ 18 years of age.

Exclusion Criteria:

  • Individuals < 18 years of age.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Paul Limburg, M.D.

Closed for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

More information

Publications

Publications are currently not available

More about research at Mayo Clinic

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CLS-20508589

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